Alzheimer’s Disease Research Grant Program


Advancing research for the 47 million people worldwide with Alzheimer’s
After 100 years of research, we still do not have a cure for Alzheimer’s disease. The majority of research funding has remained largely dedicated to long-standing, traditional methods of neurodegenerative research and is less inviting of research investigating a potential microbial link to the disease.
Intriguing evidence suggests Alzheimer’s disease may have a link to infectious diseases or a microbial mechanism. Could this be the missing link to lead to a cure?
To advance research that could shed light and provide hope to the more than 5.7 million Americans and 47 million people worldwide living with the disease, the IDSA Foundation established the Alzheimer’s Research Grant, now known as the Microbial Pathogenesis in Alzheimer’s Disease Grant, in 2018 to foster further investigation. These grants support research that suggests an infectious agent or microbial community is correlated to Alzheimer’s disease and promotes novel research in the field of microbial triggers for Alzheimer’s disease.
This program began solely as a grant-making endeavor. However, over the past 5 years, it has progressed into an established research community development program that promotes the pathogenic framework and provides support and opportunities for scientific advancement.
Who can apply
The request for applications for the Microbial Pathogenesis in Alzheimer’s Disease Research Grant Program for 2025 is closed.
This year, funding will be focused on expanding on research that has shown promise in the field of pathogenic causes of Alzheimer’s Disease and will be given to existing researchers to further their work as well as provide support for alignment between established researchers to foster collaborative discovery.
Members + nonmembers
International + non-U.S. citizens
PhDs + MDs encouraged
Clinical + basic scientists, interdisciplinary
Steps to follow
Microbial Pathogenesis in
Alzheimer’s Disease Grant FAQ
Grants provide funding to identify a potential microbial link to Alzheimer’s disease. All awards must be narrowly focused on elucidating the possible roles of infectious agents in the causation of Alzheimer’s disease. The grant awards will support innovative research including basic, clinical and/or non-traditional approaches. This includes proposals that span the breadth of the microbial world, including bacteria, fungi, parasites, viruses and microbial synergy, among other possibilities.
As long as you continue to meet the eligibility requirements, yes, you may resubmit an application.
The application for the past cycle opened on October 15, 2024. Applications closed on January 10, 2025.
If the deadline has not passed, you will be able to edit your application, even after submission. If you encounter any issues, please contact Amy Shapley-Farrell, Program Manager. She will be able to assist you.
Equipment and travel costs are not allowed in grant requests. Travel scholarships are available for some travel costs through the grant program.
No indirect costs are provided to the institution to which grants are awarded.
Total salary support for PI should not exceed 15% (this includes fringe costs):
- $100,000 level: PI salary should not exceed $15,000.
- $75,000 level: PI salary should not exceed $11,250.
Multiple investigators working on the project at the time of application is allowed, but there may only be one PI. Submission of a research proposal is required by an identified PI.
We highly recommend attending the Microbial Pathogenesis in Alzheimer’s Disease Grant informational webinar. The link can be found below under Resources.
Both members and nonmembers of IDSA are encouraged to apply. This includes established investigators and academic and health professionals in all disciplines and health-related professions.
- PhDs and MDs are welcome to apply.
- Interdisciplinary research is encouraged, including collaborations between experts in Alzheimer’s research and infectious diseases.
- Clinical and basic scientists are encouraged to apply.
- International applications and non-U.S. citizens are welcome to apply.
Requirements at which level of grant funding applicants may apply vary. The following are eligible to apply at each grant level:
- $100,000: Senior/mid-career investigators (assistant professor to professor) to established research applications at $100,000 to further existing pathogenic AD research and to facilitate development of a research proposal for submission to the NIH and/or other institutions to continue their research.
- $75,000: Team of current investigators where at least one team member is a past awardees of this grant program. Research team members have demonstrated significant progress in initial research findings and are looking to further their research through collaboration with other labs.
Yes, the grant is open to those in and outside of the U.S. Non-U.S. citizens are also eligible to apply.
Grant amounts vary each grant period, dependent on the availability of funds, merits of the project, and grant program goals for the year. The current RFA is for 5 grants:
- Three grants at $100,000 for existing research.
- Two grants at $75,000 to establish collaborative research projects between two or more researchers/ labs.
This is a competitive grant process. Over 75 applications were received the past 2 years. Sixteen individual grants were funded in 2023, ranging between $30,000 and $250,000 for a total of $2.24 million in grant funding in the 2023 grant period.
All grant applications will be checked for compliance and then reviewed by a convened expert panel with final decision by the IDSA Board of Directors.
The terms and conditions of support are available on the RFA.RFA
Resources
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RFA Microbial Pathogenesis in Alzheimer’s Disease (ID-ALZ) 2024 pdf
The Microbial Pathogenesis in Alzheimer's Disease Grant provides funding to identify a potential microbial link to Alzheimer’s disease.
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Advances in Identifying Microbial Pathogenesis in Alzheimer’s Disease link
Supplement published in The Journal of Infectious Diseases (Sept. 15, 2024)
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Microbial Pathogenesis in Alzheimer's Disease: Grantee Research Outcomes pdf
Published in 2024; grantee cycles 2018-2022
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2025 Alzheimer's Research Grants Informational Webinar link
Research grant program impact since 2018